Starting with the Sui Dynasty (581-618), the Chinese began expansion into eastern Central Asia, and had to deal with Turkic nomads, who were becoming the most dominant ethnic group in Central Asia. Originally the relationship was largely cooperative, but in 630 the Tang Dynasty began an offensive against the Turks, capturing areas of the Mongolian Ordos Desert. The Tang Empire competed with the Tibetan Empire for control of areas in Inner and Central Asia. In the 8th century, Islam began to penetrate the region and soon became the sole faith of most of the population, though Buddhism remained strong in the east. The desert nomads of Arabia could militarily match the nomads of the steppe, and the early Arab Empire gained control over parts of Central Asia.
The Hephthalites were the most powerful of the nomad groups in the 6th and 7th centuries, and controlled much of the region. In the 10th and 11th centuries the region was divided between several powerful states including the Samanid dynasty, that of the Seljuk Turks, and the Khwarezmid Empire. The most spectacular power to rise out of Central Asia developed when Genghis Khan united the tribes of Mongolia. The Mongol Empire spread to comprise all of Central Asia and China as well as large parts of Russia, and the Middle East. After Genghis Khan died in 1227, most of Central Asia continued to be dominated by the successor Chagatai Khanate. In 1369, Timur, a Turkic leader in the Mongol military tradition, conquered most of the region. Timur's large empire collapsed soon after his death, however. The region then became divided among a series of smaller Khanates, including the Khanate of Khiva, the Khanate of Bukhara, the Khanate of Kokand, and the Khanate of Kashgar.
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